Publications related with the Differentiation and Apoptosis inducing Therapy
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1. Hiçsönmez G. Short-Course High-Dose Methylprednisolone Induces Differentiation and Apoptosis
of Myeloid Leukemic Cells. Int J Stem Cell Res Ther 2016, 3(2):033.
2. Hiçsönmez G. Differentiation and Apoptosis inducing Therapy with High-dose Methylprednisolone
for non- APL Acute Myeloblastic Leukemia. J J Bone Stem Res. 2015,1(2):007. Review
3. Hiçsönmez G. High-dose glucocorticoid for the treatment of myeloid sarcoma. Journal of Leukemia
2013;1:103 doi: 10.4172/2329-6917.1000103 Review
4. Hiçsönmez G. A novel approach to treatment in childhood acute myeloblastic leukemia and
myelodysplastic syndrome with high-dose methylprednisolone as a differentiation- and apoptosis
–inducing agent of myeloid leukemic cells. Turk J Hematol. 2010;27(1):1-7. Review
5. Hiçsönmez G. The effect of steroid on myeloid leukemic cells: The potential of short-course high-
dose methylprednisolone treatment in inducing differentiation, apoptosis and in stimulatling
myelopoiesis. Leuk Res. 2006; 30(1):60-68. Review
6. Hiçsönmez G, Çetin M, Tuncer AM, Yenicesu I, Aslan D, Özyürek E, Ünal S. Children with acute
myeloblastic leukemia presenting with extramedullary infiltration: the effects of high-dose steroid
treatment. Leuk Res. 2004;28(1):25-34.
7. Hiçsönmez G, Çetin M, Okur H, Erdemli E, Gürgey A. The potential effect of short-course high-dose
steroid on the maturation and apoptosis of leukemic cells in a child with acute megakaryoblastic
leukemia. Leuk Lymphoma. 2003;44(6):1037-42.
8. Hiçsönmez G,Çetin M, Aslan D, Özyürek E. The role of short-course of high-dose
methylprednisolone in children with acute myeloblastic leukemia (FAB M2) presented with myeloid
tumor. Pediatr Hematol Oncol 2003;20:73-9.
9. Hiçsönmez G. Retinoic acid and steroid in acute promyelocytic leukemia. Leukemia.
2003;17(6):1203. Letter
10. Hiçsönmez G, Cetin M, Yenicesu I, Olcay L, Koç A, AktaÅŸ D, Tunçbilek E, Tuncer M. Evaluation of
children with myelodysplastic syndrome: importance of extramedullary disease as a presenting
symptom. Leuk Lymphoma. 2001;42(4):665-74.
11. Hiçsönmez G, Tunç B, Olcay L, Tuncer MA. Effect of short-course, high-dose steroid therapy in a
child with myelodysplastic syndrome. Pediatr Hematol Oncol. 2001;18(8):525-9.
12. Hiçsönmez G. A novel approach to treatment with high dose steroid as a differentiation inducer
in children with acute myeloblastic leukemia. Pediatric Pathology and moleculer medicine.
2000;19:251-9. Review
13. Hiçsönmez G, Tuncer M, Toksoy HB, Yenicesu I, Cetin M. Differentiation of leukemic cells induced
by short-course high-dose methylprednisolone in children with different subtypes of acute
myeloblastic leukemia. Leuk Lymphoma. 1999;33(5-6):573-80.
14. Özbek N, Erdemli E, Hiçsönmez G, Okur H, TekelioÄŸlu M. Effects of methylprednisolone on human
myeloid leukemic cells in vitro. Am J Hematol. 1999;60(4):255-9.
15. Hiçsönmez G, çetin M, Tunç B, Tuncer AM, Gümrük F, Yenicesu I. Dramatic resolution of pleural
effusion in children with chronic myelomonocytic leukemia following short-course high-dose
methylprednisolone. Leuk Lymphoma. 1998 ;29(5-6):617-23.
16. Hiçsönmez G, Gümrük F, Zamani PV, Tuncer MA, Yetgin S, Gürgey A, Atahan L, Özsoylu S. High-
dose methylprednisolone for children with acute lymphoblastic leukemia and unfavorable presenting
features. Eur J Haematol. 1997;58(1):26-31.
17. Hiçsönmez G. Effects of steroids on acute myeloblastic leukaemia. Br J Haematol.
1996;95(1):215-6. Letter
18. Hiçsönmez G, Erdemli E, Tekelioglu M, Tuncer AM, Özbek N, Cetin M, Cotter TG. Morphologic
evidence of apoptosis in childhood acute myeloblastic leukemia treated with high-dose
methylprednisolone. Leuk Lymphoma. 1996 ;22(1-2):91-6.
19. Hiçsönmez G, Özbek N, Kale G, Erdem G, Bilgiç S, Hazar V. Dramatic effect of high-dose
methylprednisolone on orbital granulocytic sarcoma. Pediatr Hematol Oncol. 1996;13(2):187-90.
20. Hiçsönmez G, Gümrük F. Giant dysplastic neutrophils: possible morphologic evidence of in vivo
differentiation of leukemia in acute myeloblastic leukemia. Am J Hematol. 1995;49(2):168-70. Letter
21. Hiçsönmez G, Tuncer AM, Cetin M, Özbek N,Gümrük F. Eight year experiences with high-dose
methylprednisolone as a differentation inducer in childhood acute myeloblastic leukemia (AML).
Challenges of Modern medicine. Differentiation therapy. 1995;10:471-5.
22. Hiçsönmez G, Cetin M, Tuncer MA, Gümrük F, Ozbek N, Kara A, Gürgey A. High-dose
methylprednisolone for remission induction in hypoplastic acute myeloid leukemia. Eur J Haematol.
1995;54(2):125-6.
23. Hiçsönmez G, Tuncer AM, Sayli T, Güler E, Çetin M, Ozbek N, Mufti GJ. High-dose
methylprednisolone, low-dose cytosine arabinoside, and mitoxantrone in children with
myelodysplastic syndromes. Hematol Pathol. 1995;9(3-4):185-93.
24. Hiçsönmez G, Tuncer AM, Güler E, Tan E, Tekelioglu M. The potential role of high-dose
methylprednisolone on the maturation of leukemic cells in children with acute promyelocytic
leukemia (APL). Exp Hematol. 1993;21(5):599-601.
25. Hiçsönmez G, Tuncer AM, Cetin M, Gümrük F, Kara A, Yalçin S. Morphologic evidence of in vivo
differentiation in acute myeloblastic leukemia. Acta Haematol. 1993;90(4):214-5. Letter
26. Hiçsönmez G, Karadeniz N, Zamani VP, Tuncer AM, Gümrük F, Erturk G, Gurgey A, Özsoylu S. High
remission rate in acute myeloblastic leukemia in children treated with high-dose
methylprednisolone. Eur J Haematol. 1992;48(4):215-20.
27. Hiçsönmez G, Ozsoylu S, Tuncer AM, Ertürk G, Ozbek N, Karadeniz N. Direct morphological
evidence of high-dose methylprednisolone-induced maturation of leukemic cells in children with
acute nonlymphoblastic leukemia. Exp Hematol. 1991;19(3):232-3.
28. Hicsonmez G, Ozsoylu S, Tuncer AM. Differentiation of myeloid leukemic cells induced by high-
dose methylprednisolone in patients with acute myeloblastic leukemia and its therapeutic potential.
Leuk Res. 1991;15(7):537-41. Review.
29. Hiçsönmez G, Özsoylu S. High-dose methylprednisolone in children with acute nonlymphoblastic
leukemia. Am J Hematol. 1990;35(4):288-9. Letter
30. Hiçsönmez G, Özsoylu S, Gürgey A, Zamani VP, Irken G. High-dose methylprednisolone for
remission induction in children with acute nonlymphoblastic leukemia. Eur J Haematol.
1989;42(5):498-500.
31. Hiçsönmez G, Ozsoylu S. High-dose methylprednisolone for acute nonlymphoblastic leukemia.
Exp Hematol. 1989;17(10):1051-2. Letter
32. Hiçsönmez G, Ozsoylu S, Tuncer M, Erer B. High-dose intravenous methylprednisolone in the
treatment of acute nonlymphoblastic leukemia with ocular involvement. Turk J Pediatr. 1988;
30(3):181-3.